Which condition can lead to increased globulin levels in blood?

Increased globulin levels in blood can often indicate an underlying condition where the immune system is activated, such as infections or inflammatory diseases. Hepatitis, which involves inflammation of the liver typically due to viral infections or other causes, can lead to this elevation. When the liver is damaged or affected, it can alter the production of proteins including globulins, which play key roles in immune responses and transport of substances in the blood. The body may increase globulin levels in response to the inflammation and immune activation associated with hepatitis, reflecting the body's attempt to deal with the underlying issue.

In contrast, dehydration primarily affects serum protein concentrations by reducing plasma volume, which can cause arbitrary increases in protein levels but does not specifically elevate globulin levels. Cardiac arrest and hypertension are also not directly related to globulin levels; they are conditions that primarily affect heart function and blood pressure regulation rather than the synthesis of proteins by the liver.